Hantavirus Contamination

Chlorine dioxide is a reliable and effective disinfectant used to decontaminate, disinfect, deodorize, or sanitize for potential hantavirus contamination. It has been found to inactivate the Hantavirus, a highly infectious virus often spread through animal urine or fecal matter (1). Chlorine dioxide is also effective against other viruses and bacteria, making it an ideal solution for decontaminating areas where Hantavirus might be present. Once dry it is non-toxic and does not leave any residue on surfaces, which makes it safe to use around people, animals, and food.

Hantavirus is a group of viruses that can cause various human diseases, including hantavirus pulmonary syndrome (HPS) and hantavirus hemorrhagic fever with renal syndrome (HFRS). It is spread by rodents such as mice, rats, and squirrels and can be found primarily in the United States and Canada.

HPS is typically characterized by mild to severe respiratory symptoms such as fever, coughing, and difficulty breathing. HFRS causes more severe symptoms such as fever, headache, abdominal pain, nausea and vomiting, muscle pain, or joint pain. It is essential to take preventive measures against potential hantavirus contamination to prevent the spread of this disease.

Chlorine dioxide is an effective way to decontaminate areas where hantavirus may be present. This chemical has been proven to kill or deactivate the virus on surfaces and in the air when used at the proper concentrations. Chlorine dioxide kills microorganisms like bacteria and viruses through oxidation, breaking down their cell walls. In addition to its effectiveness in eliminating hantaviruses, chlorine dioxide is also an effective disinfectant for other contaminants, such as mold spores and fungi, that can cause respiratory illnesses.

Moreover, chlorine dioxide can be used in many applications, including decontaminating and sanitizing food-processing equipment, disinfecting swimming pools and spas, eliminating odors from smoke or pet smells, and purifying drinking water (3). Chlorine dioxide is a highly effective solution for all types of sanitation needs.

Chlorine dioxide has been recommended for use in homes where rodents are suspected or known to have been present due to its low toxicity and long-lasting ability to kill microorganisms on surfaces. It can also be used in hospitals or schools where there could be potential hantavirus contamination from rodent feces or urine droppings left behind on floors or furniture. Using chlorine dioxide eliminates the need for harsh chemicals that may have negative environmental impacts while still providing an effective way to sanitize surfaces against potential hantavirus contamination.


Use for antimicrobial and general cleaning applications in institutional, business, medical, residential, professional, motor vehicles, fleets, boats, R.V.s, buses, HVAC, spas, filters, and as an additives applied to cleaning products (prior/simultaneous/post detergent) in a cleaning apparatus, or stand-alone spot cleaner for post-cleaning on rugs, carpeting, upholstery, without fading colors or dyed fabrics. Prepare an activated solution to a strength consistent with the maximum threshold for hard (non-porous) and soft (porous) surfaces, use as a commercial fogging agent, mechanical coarse, hand pump, surfaces in medical facilities, livestock areas, where a powerful biocide is needed, where contagious zoonotic diseases are present, to remove airborne pathogens, for water damage and mold remediation on porous, and NON-porous surfaces including concrete, asphalt, (sub)floor, carpet, and turf.

Use-SiteCONCENTRATIONMix EQUAL PARTS 1:1  –  NaClO2 (Part A) and HCl (Part B)
Light –  Non-Food Contact50 PPM50 drops A, with 50 drops B in 1 gallon of water. (2ml = 50 drops)
Heavy – Non-Food Contact300  PPM300 drops A, with 300 drops B in 1 gallon of water. (12ml = 300 drops)
HVAC – Vents and Air Ducts500 PPM500 drops A, with 500 drops B in 1 gallon of water. (20ml = 500 drops)
Insecticide or Fumigant725 PPM725 drops A, with 725 drops B in 1 gallon of water. (29ml = 725 drops)

Mix recommended strength in the corner of a designated plastic mixing container. Let the solution activate for 1 minute before dilution, then fill with water.
Agitate until mixed. Use as a solution in a manner consistent with usual standards.

  • SPRAY / FOG – allow visible wetness for 5 minutes before drying. 
  • MOP – allow visible wetness for 5 minutes before drying. 
  • SWAB / SPONGE – allow visible wetness for 5 minutes before drying. 
  • SOAK / IMMERSE  – allow to drench or submerge for 1 minute. 
  • FLUSH / FILL – allow to drench or submerge for 1 minute. 
  • DIP / RINSE – allow to drench or submerge for 1 minute. 


  1. News & Terrorism Communicating In A Crisis A Fact Sheet From The National Academies And The U.S. Department Of Homeland Security Biological Attack Human Pathogens, Biotoxins, And Agricultural Threats. 2004.
  2. University of Rochester Disinfectants for Biohazardous Materials Guidelines. Sept. 2011.
  3. 2018 GENERAL RATE APPLICATION Undertaking #26 Transcript Page 994. Oct. 2017.
  4. Contained use – Micro-organisms: Viability and susceptibility to disinfectants (Annexes). January 2013.
  5. Avian Flu and Human Pandemic Flu Summary Report—Meeting Held in Geneva, Switzerland 7-9 John H. Keene Biohaztec Associates, Midlothian, Virginia. November 2005 
  6. Chlorine Dioxide Against Coronavirus: A Revolutionary, Simple And Effective Approach. Project: Toxicity Study Of Chlorine Dioxide In Solution (Cds). Andreas Ludwig Kalcker. March 2020.
  7. CDC. Hantavirus. Centers for Disease Control and Prevention. 2019.
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